General Information

  • ID:  hor003606
  • Uniprot ID:  B3EWL4
  • Protein name:  CAPA-Periviscerokinin-2
  • Gene name:  NA
  • Organism:  Delia radicum (Cabbage root fly) (Anthomyia brassicae)
  • Family:  Periviscerokinin family
  • Source:  Animal
  • Expression:  Detected in larvae. |Expressed in the CNS and abdominal perisympathetic organs (aPSO). Not expressed in the ring gland, midgut or thoracic perisympathetic organs (tPSO) (at protein level).
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Delia (genus), Anthomyiinae (subfamily), Anthomyiidae (family), Muscoidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  AGLFAQPRL
  • Length:  9(1-9)
  • Propeptide:  AGLFAQPRL
  • Signal peptide:  NA
  • Modification:  T9 Leucine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Myotropic activity
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor003606_AF2.pdbhor003606_ESM.pdb

Physical Information

Mass: 111504 Formula: C45H73N13O11
Absent amino acids: CDEHIKMNSTVWY Common amino acids: AL
pI: 10.55 Basic residues: 1
Polar residues: 1 Hydrophobic residues: 5
Hydrophobicity: 44.44 Boman Index: -308
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 108.89
Instability Index: 2191.11 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  22848525
  • Title:  Peptidomics of the Agriculturally Damaging Larval Stage of the Cabbage Root Fly Delia Radicum (Diptera: Anthomyiidae)